Comparison of Pediatric Risk of Mortality (PRISM) and Pediatric Logistic Organ Dysfunction (PELOD) scales in pediatric intensive care unit patients: A single-center study Original Research

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Pamela Izquierdo Calahorrano
Natalia Sanchez Sanchez
Jenny Marisela Martinez Mena
Ivan Guillermo Dueñas Espín

Abstract

Introduction: The aim of the present study was to examine diagnostic tests between the PRISM III scale and the PELOD scale to predict mortality in patients admitted to the Intensive Care Unit (PICU) of the Baca Ortiz Pediatric Hospital in the period of June-December 2019.


Methods: In this retrospective observational study, mortality and the variables that make up each of the predictive scales were recorded. Descriptive and inferential statistics were applied along with calculation of the area under the ROC curve. The calibration was calculated using the Hosmer Lemeshow chi2, and the mortality rate was standardized using the statistical package STATA v16.


Results: 150 patients entered the study. 99 patients (66%) were male, and the mean age was 3 years (P25 to P75) with a range from 1 month to 14 years. The most frequent admission pathologies were postoperative disease in 43 patients (28.6%) and respiratory failure in 31 patients (21.6%). Mortality was 12.7%, and the mean hospital stay was 5 days (1 to 60 days). The PRIMS III scale had an area under the curve of 0.80 (95% CI from 0.70 to 0.90), sensitivity of 79%, and specificity of 63% with a PRISM III score of 13 points. The PELOD scale had an area under the curve of 0.7 (95% CI from 0.5 to 0.80), sensitivity of 79%, and specificity of 60% with a PELOD score of 21 points.


Conclusions: The PRISM III scale predicts mortality better than the PELOD scale in this group of pediatric patients in the first 24 hours.

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How to Cite
Izquierdo Calahorrano, P., Sanchez Sanchez , N. ., Martinez Mena, J. M., & Dueñas Espín, I. G. (2021). Comparison of Pediatric Risk of Mortality (PRISM) and Pediatric Logistic Organ Dysfunction (PELOD) scales in pediatric intensive care unit patients: A single-center study: Original Research. Ecuadorian Journal of Pediatrics, 22(2), Article 14:1-8. https://doi.org/10.52011/0111
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Original Articles
Author Biographies

Pamela Izquierdo Calahorrano, Postgraduate Departments of Pediatrics, Faculty of Medicine, Pontificia Universidad Católica del Ecuador

Medical Surgeon (MD) from the Pontificia Universidad Católica del Ecuador (Ecuador 2014), Specialist in Pediatrics from the Pontificia Universidad Católica del Ecuador (Ecuador 2021).

Natalia Sanchez Sanchez , Postgraduate Department of Pediatrics, Faculty of Medicine, Pontificia Universidad Católica del Ecuador

MEdical Doctor (MD) from Escuela Latinoamericana de Medicina (Cuba, 2013), Pediatric Specialist by Pontificia Universidad Católica del Ecuador (Ecuador 2021).

Jenny Marisela Martinez Mena, Postgraduate Department in Pediatrics, Faculty of Medicine, Pontificia Universidad Católica del Ecuador

Doctor in Medicine and Surgery (MD) from the Universidad Central del Ecuador (Ecuador 2003). Specialist in Pediatrics from the Universidad Central del Ecuador (Ecuador 2010). Specialist in Critical Medicine and Intensive Care from the Universidad Tecnológica Equinoccial (Ecuador 2019). Attending physician of the pediatric intensive care service of the Baca Ortiz Pediatric Hospital in Quito.

Ivan Guillermo Dueñas Espín, Postgraduate Department of Pediatrics, Faculty of Medicine, Pontificia Universidad Católica del Ecuador

Doctor of Medicine and Surgery from the Universidad Central del Ecuador (Ecuador, 2003). Specialist in Family Medicine from Pontificia Universidad Católica del Ecuador (Ecuador 2008). Master's Degree in Public Health from the Pompeu Fabra University (Spain, 2015). PhD in Biomedicine from the Pompeu Fabra University (Spain, 2017).